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1.
Heliyon ; 10(3): e24718, 2024 Feb 15.
Article in English | MEDLINE | ID: mdl-38317883

ABSTRACT

The appealing traits of carbon nanotubes (CNTs) encompassing mechanical and chemical steadiness, exceptional electrical and thermal conductivities, lightweight, and physiochemical reliability make them desired materials in engineering gadgets. Considering such stimulating characteristics of carbon nanotubes, our goal in the current study is to scrutinize the comparative analysis of Darcy-Forchheimer nanofluid flows containing CNTs of both types of multi and single-wall carbon nanotubes (MWCNTs, SWCNTs) immersed into two different base fluids over a stretched surface. The originality of the model being presented is the implementation of the induced magnetic field that triggers the electric conductivity of carbon nanotubes. Moreover, the envisioned model is also analyzed with homogeneous-heterogeneous (h-h) chemical reactions and heat source/sink. The second-order slip constraint is assumed at the boundary of the surface. The transmuted high-nonlinearity ordinary differential equations (ODEs) are attained from the governing set of equations via similarity transformations. The bvp4c scheme is engaged to get the numerical results. The influence of different parameters is depicted via graphs. For both CNTs, the rate of heat flux and the surface drag coefficient are calculated using tables. It is highlighted that an increase in liquid velocity is witnessed for a varied counts volume fraction of nanoparticles. Also, Single-wall water-based carbon nanotube fluid has comparatively stronger effects on concentration than the multi-walled carbon nanotubes in water-based liquid. The analysis also indicates that the rate of heat flux and the surface drag coefficient are augmented for both SWCNTs and MWCNTs for different physical parameters. The said model is also validated by comparing it with a published result.

2.
PLoS One ; 18(2): e0275340, 2023.
Article in English | MEDLINE | ID: mdl-36791145

ABSTRACT

Ranked set sampling is an alternative to simple random sampling, which uses the least amount of money and time. The ranked set sampling (RSS) is modified to obtain a more efficient and cost-effective estimator of population parameters. This paper aims to bring a more efficient and cost-effective design than stratified ranked set sampling and simple random sampling. In some distributions, the suggested method used fewer sample units than stratified ranked set sampling and gives a more efficient estimation of population parameters. In symmetric distributions, the proposed design, called "partial stratified ranked set sampling" yields an unbiased estimator of the population mean. The design is illustrated with practical data of COVID-19 confirmed cases.


Subject(s)
COVID-19 , Models, Statistical , Humans , Sampling Studies , COVID-19/epidemiology , Research Design
3.
Comput Math Methods Med ; 2022: 4148801, 2022.
Article in English | MEDLINE | ID: mdl-35898485

ABSTRACT

The COVID-19 pandemic has shocked nations due to its exponential death rates in various countries. According to the United Nations (UN), in Russia, there were 895, in Mexico 303, in Indonesia 77, in Ukraine 317, and in Romania 252, and in Pakistan, 54 new deaths were recorded on the 5th of October 2021 in the period of months. Hence, it is essential to study the future waves of this virus so that some preventive measures can be adopted. In statistics, under uncertainty, there is a possibility to use probability models that leads to defining future pattern of deaths caused by COVID-19. Based on probability models, many research studies have been conducted to model the future trend of a particular disease and explore the effect of possible treatments (as in the case of coronavirus, the effect of Pfizer, Sinopharm, CanSino, Sinovac, and Sputnik) towards a specific disease. In this paper, varieties of probability models have been applied to model the COVID-19 death rate more effectively than the other models. Among others, exponentiated flexible exponential Weibull (EFEW) distribution is pointed out as the best fitted model. Various statistical properties have been presented in addition to real-life applications by using the total deaths of the COVID-19 outbreak (in millions) in Pakistan and Afghanistan. It has been verified that EFEW leads to a better decision rather than other existing lifetime models, including FEW, W, EW, E, AIFW, and GAPW distributions.


Subject(s)
COVID-19 , Afghanistan/epidemiology , Humans , Pakistan/epidemiology , Pandemics , Probability
4.
Comput Math Methods Med ; 2022: 2658095, 2022.
Article in English | MEDLINE | ID: mdl-35082912

ABSTRACT

BACKGROUND: Fever is one of the frequently occurring diseases in human beings, and the body is said to have befallen in fever if the arterial or internal body temperature rises to 38°C. The patient who suffers from fever is either given paracetamol or tepid sponging or both. OBJECTIVE: This paper is aimed at studying the effects of the tepid sponge in normalizing the high temperature of the human body during fever. Among the various available methods for tepid sponging, the impact of holding a cool wet cloth on the forehead for reducing the fever is analyzed and pictured graphically. METHOD: For analyzing the effects of tepid sponge on the temperature distribution of the domain consisting of scalp, skull, and cerebrospinal fluid (CSF), a cool wet cloth is brought in contact with the skin allowing the heat to transfer from the brain to the wet cloth through these layers. The heat transfer in living biological tissues is different from ordinary heat transfer in other nonliving materials. Therefore, a model based on the bioheat equation has been constructed. The model has been solved by numerical methods for both steady- and unsteady-state cases. The domain, which consists of the scalp, skull, and CSF layers of the human head, has been discretized into four equal parts along the axes of the three-dimensional coordinate system. The forward difference and forward time centered space approximations were employed for numerical temperature distribution results at the nodal points. RESULTS: The effects of tepid sponge in reducing the body temperature with fever at 38°C, 39.5°C, and 41°C have been numerically calculated, and the results were pictured graphically. For transient cases, the corresponding calculations have been carried out at times t = 2 minutes, 4 minutes, and 6 minutes. CONCLUSION: Among all the available remedies to fever, tepid sponging has shown a significant effect in controlling fever.


Subject(s)
Brain/physiopathology , Fever/therapy , Models, Neurological , Body Temperature/physiology , Computational Biology , Computer Simulation , Fever/cerebrospinal fluid , Fever/physiopathology , Humans , Hydrotherapy/methods , Scalp/physiopathology , Skull/physiopathology , Textiles
5.
PeerJ ; 9: e11719, 2021.
Article in English | MEDLINE | ID: mdl-34285835

ABSTRACT

Predicting the yearly curve of the temperature, based on meteorological data, is essential for understanding the impact of climate change on humans and the environment. The standard statistical models based on the big data discretization in the finite grid suffer from certain drawbacks such as dimensionality when the size of the data is large. We consider, in this paper, the predictive region problem in functional time series analysis. We study the prediction by the shortest conditional modal interval constructed by the local linear estimation of the cumulative function of Y given functional input variable X . More precisely, we combine the k -Nearest Neighbors procedure to the local linear algorithm to construct two estimators of the conditional distribution function. The main purpose of this paper is to compare, by a simulation study, the efficiency of the two estimators concerning the level of dependence. The feasibility of these estimators in the functional times series prediction is examined at the end of this paper. More precisely, we compare the shortest conditional modal interval predictive regions of both estimators using real meteorological data.

6.
Sci Prog ; 104(2): 368504211014350, 2021.
Article in English | MEDLINE | ID: mdl-33950756

ABSTRACT

The acceptance sampling plan (ASP) is a statistical tool used in industry for quality control to determine the quality of products by selecting a specified number for testing in order to accept or reject the lot. The main objective is to develop a new ASP based on truncated life tests assuming that the lifetime follows the two parameters Quasi Shanker distribution, since this distribution showed its superiority in providing a better model for some applications than the exponential distribution. The ASP steps are carried out to find the minimum sample sizes needed to assert the certain life mean that are calculated under a given customer's risk. The operating characteristic values of the sampling plan and the producer risk values are obtained. The efficiency of the suggested plans is analyzed based on real data that is fitted to the Quasi Shanker distribution. For various values of the Quasi Shanker distribution parameters, numerical examples are presented for illustrative purposes. The results indicate that the suggested ASP provides smaller sample sizes than other competitors considered in this study. The suggested ASP has been found to provide a substantial sampling economy in terms of reducing the sample. Hence, it is recommended that the ASP can be used in industry and for future research works as double and group ASP.


Subject(s)
Commerce , Quality Control , Sample Size , Statistical Distributions
7.
J Adv Res ; 28: 1-6, 2021 Feb.
Article in English | MEDLINE | ID: mdl-33364039

ABSTRACT

INTRODUCTION: The concentration of fluid and its analysis in human skin is innately a challenge due to its continuous movement and involvement in maximum life processes. The concentration of the fluid gets affected by the diffusion of fluids through the skin, which acts as the main barrier between the human body and the external environment. Therefore, it becomes imperative to study the process and impact of the diffusion of fluids through the skin. The problem becomes more interesting when the human body is immersed in water. OBJECTIVES: The present paper studies the change in the fluid distribution of human skin during its immersion in water of different temperatures. The application part of the paper visualizes various impaired vascular function and muscle soreness by water immersion during the physiotherapy treatment. METHODS: A mathematical model based on the two-dimensional diffusion equation, along with appropriate boundary conditions, has been formulated. The maximum of the relevant parameters, such as fluid regulation, transfer coefficient, evaporation rate, etc., influencing the fluid distribution, have been incorporated. The model has been solved by variational finite element method, and numerical results have been obtained by the Crank-Nicholson scheme. RESULTS: The increase in fluid concentration due to treatment with cold and acute hot water immersion has been noted, and the role of water immersion in enhancing the recovery in exercise-induced muscular damage has been analyzed. CONCLUSIONS: The paper addressed the issue of rate of water diffusion through human skin, which otherwise couldn't be drawn from the analogy of gas diffusion through the membrane due to the variation in permeabilities of the two processes. The paper has applications in water immersion therapies and other activities like monitoring swimming induced pulmonary edema, etc.

8.
Comput Math Methods Med ; 2020: 3154908, 2020.
Article in English | MEDLINE | ID: mdl-32211053

ABSTRACT

This paper develops a model to identify the role of perspiration in temperature distribution of human skin. The model has been solved by using the energy balance equation on the surface of human skin. The role played by thermal conductance, convection, and heat radiation during heat transfer in human skin has been considered, and the relevant laws such as Fourier law for conduction, Newton's Law for convection, and Stefan-Boltzmann's law for radiation have been used in the model. Pennes' bioheat equation has been employed to estimate the heat flow in the dermal region of skin including subcutaneous tissue.


Subject(s)
Models, Biological , Skin Physiological Phenomena , Skin Temperature/physiology , Sweating/physiology , Body Temperature Regulation/physiology , Computational Biology , Computer Simulation , Energy Metabolism , Humans , Mathematical Concepts , Thermal Conductivity
9.
Comput Intell Neurosci ; 2019: 8640218, 2019.
Article in English | MEDLINE | ID: mdl-31885532

ABSTRACT

Genetic algorithms (GAs) are stochastic-based heuristic search techniques that incorporate three primary operators: selection, crossover, and mutation. These operators are supportive in obtaining the optimal solution for constrained optimization problems. Each operator has its own benefits, but selection of chromosomes is one of the most essential operators for optimal performance of the algorithms. In this paper, an improved genetic algorithm-based novel selection scheme, i.e., stairwise selection (SWS) is presented to handle the problems of exploration (population diversity) and exploitation (selection pressure). For its global performance, we compared with several other selection schemes by using ten well-known benchmark functions under various dimensions. For a close comparison, we also examined the significance of SWS based on the statistical results. Chi-square goodness of fit test is also used to evaluate the overall performance of the selection process, i.e., mean difference between observed and expected number of offspring. Hence, the overall empirical results along with graphical representation endorse that the SWS outperformed in terms of robustness, stability, and effectiveness other competitors through authentication of performance index (PI).


Subject(s)
Algorithms , Models, Genetic , Stochastic Processes
10.
PeerJ ; 7: e7183, 2019.
Article in English | MEDLINE | ID: mdl-31304058

ABSTRACT

Due to non-stationary and noise characteristics of river flow time series data, some pre-processing methods are adopted to address the multi-scale and noise complexity. In this paper, we proposed an improved framework comprising Complete Ensemble Empirical Mode Decomposition with Adaptive Noise-Empirical Bayesian Threshold (CEEMDAN-EBT). The CEEMDAN-EBT is employed to decompose non-stationary river flow time series data into Intrinsic Mode Functions (IMFs). The derived IMFs are divided into two parts; noise-dominant IMFs and noise-free IMFs. Firstly, the noise-dominant IMFs are denoised using empirical Bayesian threshold to integrate the noises and sparsities of IMFs. Secondly, the denoised IMF's and noise free IMF's are further used as inputs in data-driven and simple stochastic models respectively to predict the river flow time series data. Finally, the predicted IMF's are aggregated to get the final prediction. The proposed framework is illustrated by using four rivers of the Indus Basin System. The prediction performance is compared with Mean Square Error, Mean Absolute Error (MAE) and Mean Absolute Percentage Error (MAPE). Our proposed method, CEEMDAN-EBT-MM, produced the smallest MAPE for all four case studies as compared with other methods. This suggests that our proposed hybrid model can be used as an efficient tool for providing the reliable prediction of non-stationary and noisy time series data to policymakers such as for planning power generation and water resource management.

11.
Eur Biophys J ; 48(4): 383-393, 2019 May.
Article in English | MEDLINE | ID: mdl-31028435

ABSTRACT

Ion channel data recorded using the patch clamp technique are low-pass filtered to remove high-frequency noise. Almanjahie et al. (Eur Biophys J 44:545-556, 2015) based statistical analysis of such data on a hidden Markov model (HMM) with a moving average adjustment for the filter but without correlated noise, and used the EM algorithm for parameter estimation. In this paper, we extend their model to include correlated noise, using signal processing methods and deconvolution to pre-whiten the noise. The resulting data can be modelled as a standard HMM and parameter estimates are again obtained using the EM algorithm. We evaluate this approach using simulated data and also apply it to real data obtained from the mechanosensitive channel of large conductance (MscL) in Escherichia coli. Estimates of mean conductances are comparable to literature values. The key advantages of this method are that it is much simpler and computationally considerably more efficient than currently used HMM methods that include filtering and correlated noise.


Subject(s)
Computational Biology/methods , Data Analysis , Markov Chains , Algorithms , Escherichia coli Proteins/metabolism , Ion Channels/metabolism
12.
Eur Biophys J ; 44(7): 545-56, 2015 Oct.
Article in English | MEDLINE | ID: mdl-26233758

ABSTRACT

The gating behaviour of a single ion channel can be described by hidden Markov models (HMMs), forming the basis for statistical analysis of patch clamp data. Extensive improved bandwidth (25 kHz, 50 kHz) data from the mechanosensitive channel of large conductance in Escherichia coli  were analysed using HMMs, and HMMs with a moving average adjustment for filtering. The aim was to determine the number of levels, and mean current, mean dwell time and proportion of time at each level. Parameter estimates for HMMs with a moving average adjustment for low-pass filtering were obtained using an expectation-maximisation algorithm that depends on a generalisation of Baum's forward-backward algorithm. This results in a simpler algorithm than those based on meta-states and a much smaller parameter space; hence, the computational load is substantially reduced. In addition, this algorithm maximises the actual log-likelihood rather than that for a related meta-state process. Comprehensive data analyses and comparisons across all our data sets have consistently shown five subconducting levels in addition to the fully open and closed levels for this channel.


Subject(s)
Escherichia coli Proteins/chemistry , Ion Channel Gating , Ion Channels/chemistry , Escherichia coli Proteins/metabolism , Ion Channels/metabolism , Markov Chains , Models, Theoretical
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